Modulation of the Activity of Mycobacterium tuberculosis LipY by Its PE Domain.

Mycobacterium tuberculosis harbors over 160 genes encoding PE/PPE proteins, several of which have roles in the pathogen's virulence. A number of PE/PPE proteins are secreted via Type VII secretion systems known as the ESX secretion systems. One PE protein, LipY, has a triglyceride lipase domain...

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Bibliographic Details
Main Authors: Christopher K Garrett, Lindsey J Broadwell, Cassandra K Hayne, Saskia B Neher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4536007?pdf=render