Alkyne-Tagged Apigenin, a Chemical Tool to Navigate Potential Targets of Flavonoid Anti-Dengue Leads

Alkyne-Tagged Apigenin, a Chemical Tool to Navigate Potential Targets of Flavonoid Anti-Dengue Leads

A flavonoid is a versatile core structure with various cellular, immunological, and pharmacological effects. Recently, flavones have shown anti-dengue activities by interfering with viral translation and replication. However, the molecular target is still elusive. Here we chemically modified apigeni...

Full description

Bibliographic Details
Main Authors: Kowit Hengphasatporn, Benyapa Kaewmalai, Somruedee Jansongsaeng, Vishnu Nayak Badavath, Thanaphon Saelee, Thamonwan Chokmahasarn, Tanatorn Khotavivattana, Yasuteru Shigeta, Thanyada Rungrotmongkol, Siwaporn Boonyasuppayakorn
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
alkyne-tagged flavonoid
dengue virus
drug discovery
alkyne-azide cycloaddition
flavone
target identification
Online Access:https://www.mdpi.com/1420-3049/26/22/6967

Internet

https://www.mdpi.com/1420-3049/26/22/6967

Similar Items