The role of WT1 in breast and other cancers: oncogene or tumor suppressor gene?
The Wilms' tumor 1 (WT1) gene is originally identified in Wilms tumor, a childhood kidney cancer. This gene encodes a zinc finger transcriptional regulatory protein that has been implicated in growth, normal development, survival and apoptosis. Alternative splicing of the WT1 transcript generat...
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Format: | Article |
Language: | English |
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Prince of Songkla University
2009-10-01
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Series: | Journal of Health Science and Medical Research (JHSMR) |
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Online Access: | https://www.jhsmr.org/index.php/jhsmr/article/view/409 |