Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds.

Virus ecology and evolution play a central role in disease emergence. However, their relative roles will vary depending on the viruses and ecosystems involved. We combined field studies, phylogenetics and experimental infections to document with unprecedented detail the stages that precede initial o...

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Main Authors: Henan Zhu, Batchuluun Damdinjav, Gaelle Gonzalez, Livia Victoria Patrono, Humberto Ramirez-Mendoza, Julien A R Amat, Joanna Crispell, Yasmin Amy Parr, Toni-Ann Hammond, Enkhtuvshin Shiilegdamba, Y H Connie Leung, Malik Peiris, John F Marshall, Joseph Hughes, Martin Gilbert, Pablo R Murcia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007531