Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis

Corticosterone is known to accumulate in brain after various stressors including alcohol intoxication. Just as severe alcohol intoxication is typically required to impair memory formation only high concentrations of ethanol (60mM) acutely inhibit long-term potentiation (LTP), a cellular memory mech...

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Bibliographic Details
Main Authors: Yukitoshi eIzumi, Kazuko A. O’Dell, Charles F. Zorumski
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00254/full