A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression [version 2; referees: 2 approved]

One commonly performed bioinformatics task is to infer functional regulation of transcription factors by observing differential expression under a knockout, and integrating DNA binding information of that transcription factor.   However, until now, this task has required dedicated bioinformatics sup...

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Bibliographic Details
Main Authors: Daniel Carlin, Kassi Kosnicki, Sara Garamszegi, Trey Ideker, Helga Thorvaldsdóttir, Michael Reich, Jill Mesirov
Format: Article
Language:English
Published: F1000 Research Ltd 2018-01-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-784/v2