Population pharmacokinetics of atacicept in systemic lupus erythematosus: An analysis of three clinical trials

Abstract B cell stimulating factor (BLyS) and a proliferation‐inducing ligand (APRIL) are targets for novel treatments in patients with systemic lupus erythematosus (SLE). Atacicept is a recombinant, soluble fusion protein that blocks BLyS and APRIL activity. This study characterized the pharmacokin...

Full description

Bibliographic Details
Main Authors: Maria Pitsiu, Özkan Yalkinoglu, Colm Farrell, Pascal Girard, Cristina Vazquez‐Mateo, Orestis Papasouliotis
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12982