Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis.

Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis.

Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, as well as for their maintenance in the adult. Homeobox genes comprise an important family of transcription factors, which are characterised by a well conserved DNA binding motif; the homeodomain. The...

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Bibliographic Details
Main Authors: Padma eMurthi, Mohamed eAbumaree, Bill eKalionis
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Pharmacology
Subjects:
Endothelial Cells
Placenta
Transcription Factors
Angiogenesis
homeobox gene
microvasculature
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00133/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00133/full

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