Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations

Long-term colonization of the cystic fibrosis lung by Burkholderia cepacia complex bacteria: epidemiology, clonal variation and genome-wide expression alterations

Long-term respiratory infections with Burkholderia cepacia complex (Bcc) bacteria in cystic fibrosis (CF) patients generally lead to a more rapid decline in lung function and, in some cases, to a fatal necrotizing pneumonia known as the cepacia syndrome. Bcc bacteria are ubiquitous in the environmen...

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Bibliographic Details
Main Authors: Carla Patrícia Coutinho, Sandra Costa dos Santos, Andreia eMadeira, Nuno Pereira Mira, Ana Sílvia Moreira, Isabel eSá-Correia
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Burkholderia cenocepacia
Burkholderia cepacia complex
Cystic Fibrosis
chronic respiratory infection
clonal variation
genome-wide expression
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00012/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00012/full

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