Structural visualization of key steps in nucleosome reorganization by human FACT

Structural visualization of key steps in nucleosome reorganization by human FACT

Abstract Facilitates chromatin transcription (FACT) is a histone chaperone, which accomplishes both nucleosome assembly and disassembly. Our combined cryo-electron microscopy (EM) and native mass spectrometry (MS) studies revealed novel key steps of nucleosome reorganization conducted by a Mid domai...

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Bibliographic Details
Main Authors: Kouta Mayanagi, Kazumi Saikusa, Naoyuki Miyazaki, Satoko Akashi, Kenji Iwasaki, Yoshifumi Nishimura, Kosuke Morikawa, Yasuo Tsunaka
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-46617-7

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