Characterization of the Jomthonic Acids Biosynthesis Pathway and Isolation of Novel Analogues in Streptomyces caniferus GUA-06-05-006A
Jomthonic acids (JAs) are a group of natural products (NPs) with adipogenic activity. Structurally, JAs are formed by a modified β-methylphenylalanine residue, whose biosynthesis involves a methyltransferase that in Streptomyces hygroscopicus has been identified as MppJ. Up to date, three JA members...
Main Authors: | Raúl García-Salcedo, Rubén Álvarez-Álvarez, Carlos Olano, Librada Cañedo, Alfredo F. Braña, Carmen Méndez, Fernando de la Calle, José A. Salas |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-07-01
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Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/16/8/259 |
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