Identification of a VHL gene mutation in atypical Von Hippel-Lindau syndrome: genotype–phenotype correlation and gene therapy perspective

Identification of a VHL gene mutation in atypical Von Hippel-Lindau syndrome: genotype–phenotype correlation and gene therapy perspective

Abstract Background Classical von Hippel Lindau (VHL) disease/syndrome includes CNS hemangioblastoma, renal or pancreatic cysts, pheochromocytoma, renal carcinoma and exodermic cystadenoma. The syndrome is caused by mutation of VHL tumor suppressor gene. The most prevalent mutations are present in V...

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Bibliographic Details
Main Authors: Dali Tong, Yao Zhang, Jun Jiang, Gang Bi
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Cancer Cell International
Subjects:
Von Hippel Lindau (VHL)
Gene mutation
Carcinoid
Neuroendocrine tumor
Online Access:https://doi.org/10.1186/s12935-021-02386-w

Internet

https://doi.org/10.1186/s12935-021-02386-w

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