GENE-IS: Time-Efficient and Accurate Analysis of Viral Integration Events in Large-Scale Gene Therapy Data

Integration site profiling and clonality analysis of viral vector distribution in gene therapy is a key factor to monitor the fate of gene-corrected cells, assess the risk of malignant transformation, and establish vector biosafety. We developed the Genome Integration Site Analysis Pipeline (GENE-IS...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Saira Afzal, Stefan Wilkening, Christof von Kalle, Manfred Schmidt, Raffaele Fronza
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2017-03-01
Seri Bilgileri:Molecular Therapy: Nucleic Acids
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2162253116303638