Favorably against the odds - autophagy control despite advanced amyloid- ß toxicity

Alzheimer disease (AD) is a devastating condition associated with loss of proteostasis control and autophagy failure, leading to progressive neuronal cell death. However, the relationship between the activity in macroautophagy (MA) and chaperone-mediated autophagy (CMA) in the context of cargo clear...

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Bibliographic Details
Main Authors: Claudia M Ntsapi, Andre du Toit, Ben Loos
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Autophagy Reports
Subjects:
Online Access:http://dx.doi.org/10.1080/27694127.2022.2082631