Conformational analysis of isolated domains of Helicobacter pylori CagA.

The CagA protein of Helicobacter pylori is associated with increased virulence and gastric cancer risk. CagA is translocated into the host cell by a H. pylori type IV secretion system via mechanisms that are poorly understood. Translocated CagA interacts with numerous host factors, altering a variet...

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Bibliographic Details
Main Authors: Amanda P Woon, Abolghasem Tohidpour, Hernan Alonso, Yumiko Saijo-Hamano, Terry Kwok, Anna Roujeinikova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24223932/?tool=EBI