Differential involvement of cAMP/PKA-, PLC/PKC- and Ca2+/calmodulin-dependent pathways in GnRH-induced prolactin secretion and gene expression in grass carp pituitary cells

Differential involvement of cAMP/PKA-, PLC/PKC- and Ca2+/calmodulin-dependent pathways in GnRH-induced prolactin secretion and gene expression in grass carp pituitary cells

Gonadotropin-releasing hormone (GnRH) is a key stimulator for gonadotropin secretion in the pituitary and its pivotal role in reproduction is well conserved in vertebrates. In fish models, GnRH can also induce prolactin (PRL) release, but little is known for the corresponding effect on PRL gene expr...

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Bibliographic Details
Main Authors: Wensheng Li, Cheng Ye, Mulan He, Wendy K. W. Ko, Christopher H. K. Cheng, Ying Wai Chan, Anderson O. L. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Endocrinology
Subjects:
GnRH
prolactin
hormone secretion
gene expression
signal transduction
pituitary cells
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1399274/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1399274/full

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