Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity

Design of the Building Research in CRC prevention (BRIDGE-CRC) trial: a 6-month, parallel group Mediterranean diet and weight loss randomized controlled lifestyle intervention targeting the bile acid-gut microbiome axis to reduce colorectal cancer risk among African American/Black adults with obesity

Abstract Background Among all racial/ethnic groups, people who identify as African American/Blacks have the second highest colorectal cancer (CRC) incidence in the USA. This disparity may exist because African American/Blacks, compared to other racial/ethnic groups, have a higher prevalence of risk...

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Bibliographic Details
Main Authors: Andrew McLeod, Patricia Wolf, Robert S. Chapkin, Laurie A. Davidson, Ivan Ivanov, Michael Berbaum, Lauren R. Williams, H. Rex Gaskins, Jason Ridlon, Jen Sanchez-Flack, Lara Blumstein, Linda Schiffer, Alyshia Hamm, Kate Cares, Mirjana Antonic, Beatriz Penalver Bernabe, Marian Fitzgibbon, Lisa Tussing-Humphreys
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Trials
Subjects:
Cancer health disparities
Colorectal cancer
Mediterranean diet
Weight loss
Gut microbiome
Bile acids
Online Access:https://doi.org/10.1186/s13063-023-07115-4

Internet

https://doi.org/10.1186/s13063-023-07115-4

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