Inhomogeneously distributed ferroptosis with a high peak-to-valley ratio may improve the antitumor immune response

Combined radiotherapy (RT) and mild hyperthermia have been used clinically for decades to increase local control. Both modalities tend to achieve a homogeneous dose distribution within treatment targets to induce immunogenic cell death. However, marked, and long-lasting abscopal effects have not usu...

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Bibliographic Details
Main Authors: Mau-Shin Chi, Der-Chi Tien, Kwan-Hwa Chi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1178681/full