EXPRESSION AND CLINICAL CORRELATION OF PD-1/PD-L1 AND VE1(BRAFP.V600E) IN PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS

EXPRESSION AND CLINICAL CORRELATION OF PD-1/PD-L1 AND VE1(BRAFP.V600E) IN PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS

Background: Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasm with a wide spectrum of clinical presentations. Programmed Cell Death-1 (PD-1) receptor and its ligand (PD-L1)   are overexpressed in LCH, but their clinical significance is unknown. We performed a clinical correlat...

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Bibliographic Details
Main Authors: sneha tandon, Sheila Weitzman, Brooklyn Joyce, Bryan Maguire, Derek Stephens, James Whitlock, Cynthia Hawkins, Bo-Yee Ngan, Oussama Abla
Format: Article
Language:English
Published: PAGEPress Publications 2023-04-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Langerhans cell histiocytosis
Paediatric
PD-1
PD-L1
VE1(BRAFp.V600E)
Histiocytosis
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/5164

Internet

http://www.mjhid.org/index.php/mjhid/article/view/5164

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