Decrease in plasma levels of α-synuclein is evident in patients with Parkinson's disease after elimination of heterophilic antibody interference.

Decrease in plasma levels of α-synuclein is evident in patients with Parkinson's disease after elimination of heterophilic antibody interference.

There is substantial biochemical, pathological, and genetic evidence that α-synuclein (A-syn) is a principal molecule in the pathogenesis of Parkinson disease (PD). We previously reported that total A-syn levels in cerebrospinal fluid (CSF), measured with the specific enzyme-linked immunosorbent ass...

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Bibliographic Details
Main Authors: Ryotaro Ishii, Takahiko Tokuda, Harutsugu Tatebe, Takuma Ohmichi, Takashi Kasai, Masanori Nakagawa, Toshiki Mizuno, Omar M A El-Agnaf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0123162

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https://doi.org/10.1371/journal.pone.0123162

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