SYNTHESIS OF CALIX[4]ARENES WITH FIXED CONFORMATION AS POTENTIAL INHIBITORS OF FIBRIN POLYMERIZATION

Aim. The purpose of the present study was to develop a method for the fixation of ‘fixed’ conformation for estimation of the impact of calix[4]arene structure on the efficacy of its anticoagulant activity. This was achieved by substitution of the lower rim of C-145 analogue. Methods.Calix[4]arene...

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Bibliographic Details
Main Authors: D.M. Ahishev, O.O. Hrabovskyi
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2023-04-01
Series:Biotechnologia Acta
Subjects:
Online Access:https://biotechnology.kiev.ua/images/BTA/2023/2_2023/Ahishev_2_2023.pdf