Supramolecular Polymer‐Nanomedicine Hydrogel Loaded with Tumor Associated Macrophage‐Reprogramming polyTLR7/8a Nanoregulator for Enhanced Anti‐Angiogenesis Therapy of Orthotopic Hepatocellular Carcinoma

Supramolecular Polymer‐Nanomedicine Hydrogel Loaded with Tumor Associated Macrophage‐Reprogramming polyTLR7/8a Nanoregulator for Enhanced Anti‐Angiogenesis Therapy of Orthotopic Hepatocellular Carcinoma

Abstract Anti‐angiogenic therapies targeting inhibition of vascular endothelial growth factor (VEGF) pathway show clinical benefit in hypervascular hepatocellular carcinoma (HCC) tumors. However, HCC expresses massive pro‐angiogenic factors in the tumor microenvironment (TME) in response to anti‐ang...

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Bibliographic Details
Main Authors: Xiang Liu, Yini Huangfu, Jingrong Wang, Pengxu Kong, Weijun Tian, Peng Liu, Chuang Fang, Shuangyang Li, Yu Nie, Zujian Feng, Pingsheng Huang, Shengbin Shi, Chuangnian Zhang, Anjie Dong, Weiwei Wang
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
anti‐angiogenic therapy
nanoregulator
orthotopic hepatocellular carcinoma
supramolecular hydrogel
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202300637

Internet

https://doi.org/10.1002/advs.202300637

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