The Role of the L-Arginine–Nitric Oxide Molecular Pathway in Autosomal Dominant Polycystic Kidney Disease

The Role of the L-Arginine–Nitric Oxide Molecular Pathway in Autosomal Dominant Polycystic Kidney Disease

Recently, arginine has been proven to play an important role in ADPKD physiopathology. Arginine auxotrophy in ADPKD induces cell hyperproliferation, blocking the normal differentiation of renal tube cells and causing cyst formation. We explored the L-arginine (Arg)–nitric oxide (NO) molecular pathwa...

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Bibliographic Details
Main Authors: Corina Daniela Ene, Mircea Penescu, Ilinca Nicolae, Cristina Capusa
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Personalized Medicine
Subjects:
arginine auxotrophy
autosomal dominant polycystic kidney disease
cystogenesis
inducible nitric oxide synthase
arginase 2
nitric oxide metabolites
Online Access:https://www.mdpi.com/2075-4426/14/3/299

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https://www.mdpi.com/2075-4426/14/3/299

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