Attenuation of Morphine Physical Dependence and Blood Levels of Cortisol by Central and Systemic Administration of Ramelteon in Rat

Background: Chronic administration of morphine cause physical dependence but the exact mechanism of this phenomenon remains unclear. The aim of this study is the assessment of systemic and intracerebroventricular (icv) administration of ramelteon (a melatonin receptor agonist) on morphine physical d...

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Bibliographic Details
Main Authors: Majid Motaghinejad, Ozra Motaghinejad, Pantea Hosseini
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-05-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/825