Leishmania Exosomes Deliver Preemptive Strikes to Create an Environment Permissive for Early Infection

Herein, we review evidence supporting a role for leishmania exosomes during early infection. We suggest a model in which leishmania secreted microvesicles released into the extracellular milieu deliver effector cargo to host target cells. This cargo mediates immunosuppression and functionally primes...

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Bibliographic Details
Main Authors: Judith Maxwell Silverman, Neil Eugene Reiner
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2011.00026/full