Role of pelitinib in the regulation of migration and invasion of hepatocellular carcinoma cells via inhibition of Twist1

Abstract Background Overexpression of Twist1, one of the epithelial-mesenchymal transition-transcription factors (EMT-TFs), is associated with hepatocellular carcinoma (HCC) metastasis. Pelitinib is known to be an irreversible epidermal growth factor receptor tyrosine kinase inhibitor that is used i...

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Bibliographic Details
Main Authors: Sewoong Lee, Eunjeong Kang, Unju Lee, Sayeon Cho
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11217-2