Down-regulating sphingolipid synthesis increases yeast lifespan.
Knowledge of the mechanisms for regulating lifespan is advancing rapidly, but lifespan is a complex phenotype and new features are likely to be identified. Here we reveal a novel approach for regulating lifespan. Using a genetic or a pharmacological strategy to lower the rate of sphingolipid synthes...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3271065?pdf=render |