Placenta mediates the effect of maternal hypertension polygenic score on offspring birth weight: a study of birth cohort with fetal growth velocity data

Placenta mediates the effect of maternal hypertension polygenic score on offspring birth weight: a study of birth cohort with fetal growth velocity data

Abstract Background Low birth weight (LBW) and fetal growth restriction are associated with the development of cardio-metabolic diseases later in life. A recent Mendelian randomization study concluded that the susceptibility of LBW infants to develop hypertension during adulthood is due to the inher...

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Bibliographic Details
Main Authors: Noriko Sato, Ayako Fudono, Chihiro Imai, Hidemi Takimoto, Iori Tarui, Tomoko Aoyama, Satoshi Yago, Motoko Okamitsu, Shuki Mizutani, Naoyuki Miyasaka
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Medicine
Subjects:
Intrauterine programming
Placenta
Blood pressure
Vascular genes
Developmental Origin of Health and Disease (DOHaD)
Online Access:https://doi.org/10.1186/s12916-021-02131-0

Internet

https://doi.org/10.1186/s12916-021-02131-0

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