Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study

Abstract The relationship between microbiota, short chain fatty acids (SCFAs), and obesity remains enigmatic. We employ amplicon sequencing and targeted metabolomics in a large (n = 1904) African origin cohort from Ghana, South Africa, Jamaica, Seychelles, and the US. Microbiota diversity and fecal...

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Bibliographic Details
Main Authors: Gertrude Ecklu-Mensah, Candice Choo-Kang, Maria Gjerstad Maseng, Sonya Donato, Pascal Bovet, Bharathi Viswanathan, Kweku Bedu-Addo, Jacob Plange-Rhule, Prince Oti Boateng, Terrence E. Forrester, Marie Williams, Estelle V. Lambert, Dale Rae, Nandipha Sinyanya, Amy Luke, Brian T. Layden, Stephen O’Keefe, Jack A. Gilbert, Lara R. Dugas
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40874-x