P11 The Role of Smooth Muscle Integrin Alpha V and TGF-Beta Pathways in Vascular Fibrosis

It has been demonstrated that arterial stiffness is linked to arterial fibrosis manifested by increased collagen and other extracellular matrix synthesis in smooth muscle cells (SMC). Transmembrane receptors integrins mediating cell-cell and cell-matrix signalling pathways are involved in tissue fib...

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Bibliographic Details
Main Authors: Alexandre Raoul, Ekaterina Belozertseva, Huguette Louis, Zhenlin Li, Veronique Regnault, Patrick Lacolley
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125934424/view