Darier’s disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour

Darier’s disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour

Abstract Background Darier’s disease (DD) is a genodermatosis caused by mutations of the ATP2A2 gene leading to disrupted keratinocyte adhesion. Recurrent episodes of skin inflammation and infections with a typical malodour in DD indicate a role for microbial dysbiosis. Here, for the first time, we...

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Bibliographic Details
Main Authors: Yacine Amar, Danielle Rogner, Rafaela L. Silva, Bärbel U. Foesel, Minhaz Ud-Dean, Ilias Lagkouvardos, Susanne A. Steimle-Grauer, Sebastian Niedermeier, Susanne Kublik, Manja Jargosch, Matthias Heinig, Jenny Thomas, Stefanie Eyerich, Jakob D. Wikström, Michael Schloter, Kilian Eyerich, Tilo Biedermann, Martin Köberle
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Microbiome
Subjects:
Genodermatosis
Darier’s disease
Skin barrier
Malodour
Microbiome
Transcriptome
Online Access:https://doi.org/10.1186/s40168-023-01587-x

Internet

https://doi.org/10.1186/s40168-023-01587-x

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