Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE)

Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE)

HtrA1, Ddr-2 and Mmp-13 are reliable biomarkers for osteoarthritis (OA), yet the exact mechanism for the upregulation of HtrA-1 is unknown. Some have shown that chondrocyte hypertrophy is associated with early indicators of inflammation including TGF- and the Receptor for Advanced Glycation End pro...

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Bibliographic Details
Main Authors: D. Justin Larkin, Jeffrey Z. Kartchner, Alexander S. Doxey, Weston R. Hollis, Jeffrey L. Rees, Spencer K. Wilhelm, Christian S. Draper, Danielle M. Peterson, Gregory G. Jackson, Chelsey eIngersoll, S. Scott Haynie, Elizabeth eChavez, Paul R Reynolds, David L Kooyman
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Physiology
Subjects:
Inflammation
Osteoarthritis
Rage
TGF-1
HtrA-1
Ddr-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00121/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00121/full

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