Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy

Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy

BackgroundEpilepsy is a serious health problem worldwide. Despite the introduction of new antiepileptic drugs (AEDs) almost 30% of these patients have drug-resistant forms of the disease (DRE), with a significant increase in morbi-mortality.ObjectiveOur objective was to assess the impact of some gen...

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Bibliographic Details
Main Authors: Carlos Alberto Calderon-Ospina, Jubby Marcela Galvez, Claudia López-Cabra, Natalia Morales, Carlos Martín Restrepo, Jesús Rodríguez, Fabio Ancízar Aristizábal-Gutiérrez, Alberto Velez-van-Meerbeke, Paul Laissue, Dora Janeth Fonseca-Mendoza
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
drug resistant epilepsy
phenytoin
drug-related side effects and adverse reactions
pharmacovigilance
pharmacogenetics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00555/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.00555/full

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