SIRT3 activation promotes enteric neurons survival and differentiation
Abstract Enteric neuron degeneration has been observed during aging, and in individuals with metabolic dysfunction including obesity and diabetes. Honokiol, a naturally occurring compound, is an activator of Sirtuin-3 (SIRT3) that has antioxidant activity. Its role in modulating enteric neuron-speci...
Main Authors: | Arun Balasubramaniam, Ge Li, Anita Ramanathan, Simon Musyoka Mwangi, C. Michael Hart, Jack L. Arbiser, Shanthi Srinivasan |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-26634-9 |
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