Immunomodulatory Effect of Colistin and its Protective Role in Rats with Methicillin-Resistant Staphylococcus aureus-induced Pneumonia

Immunomodulatory Effect of Colistin and its Protective Role in Rats with Methicillin-Resistant Staphylococcus aureus-induced Pneumonia

Objectives: Colistin is the last resort of antimicrobials against multi-drug resistant Gram-negative pathogens. Previous studies in Caenorhabditis elegans and macrophages of rats have suggested that colistin possesses the immunomodulatory properties by acting p38/MAPK pathway. Here, we aimed to conf...

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Bibliographic Details
Main Authors: Hui Niu, Tianli Yang, Jin Wang, Rui Wang, Yun Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
colistin (MeSH)
immunomodulatory
MRSA
pneumonia
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.602054/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.602054/full

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