Autofluorescence-based tissue characterization enhances clinical prospects of light-sheet-microscopy

Abstract Light sheet fluorescence microscopy (LSFM) is a transformative imaging method that enables the visualization of non-dissected specimen in real-time 3D. Optical clearing of tissues is essential for LSFM, typically employing toxic solvents. Here, we test the applicability of a non-hazardous a...

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Bibliographic Details
Main Authors: Alice M. Jacob, Anna F. Lindemann, Julia Wagenpfeil, Sergej Geiger, Yannik C. Layer, Babak Salam, Sarah Panahabadi, Darius Kurt, Maximilian W. M. Wintergerst, Frank A. Schildberg, Daniel Kuetting, Ulrike I. Attenberger, Zeinab Abdullah, Alexander M. C. Böhner
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-67366-2