Protocol for investigating tertiary lymphoid structures in human and murine fixed tissue sections using Opal™-TSA multiplex immunohistochemistry

Summary: Tertiary lymphoid structures (TLSs) are ectopic lymphoid aggregates that can develop within or adjacent to tumors, but protocols that can accurately identify and characterize TLSs are lacking. Here, we present a protocol for the in situ interrogation and characterization of TLSs in human an...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Luke T. Quigley, Lokman Pang, Elnaz Tavancheh, Matthias Ernst, Andreas Behren, Jennifer Huynh, Jessica Da Gama Duarte
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Elsevier 2023-03-01
Цуврал:STAR Protocols
Нөхцлүүд:
Онлайн хандалт:http://www.sciencedirect.com/science/article/pii/S2666166722008413