Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome.

<h4>Background</h4>Down syndrome (DS) individuals suffer mental retardation with further cognitive decline and early onset Alzheimer's disease.<h4>Methodology/principal findings</h4>To understand how trisomy 21 causes these neurological abnormalities we investigated chan...

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Bibliographic Details
Main Authors: Chelsee A Hewitt, King-Hwa Ling, Tobias D Merson, Ken M Simpson, Matthew E Ritchie, Sarah L King, Melanie A Pritchard, Gordon K Smyth, Tim Thomas, Hamish S Scott, Anne K Voss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20661276/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20661276/?tool=EBI

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