Dihydroartemisinin Sensitizes Lung Cancer Cells to Cisplatin Treatment by Upregulating ZIP14 Expression and Inducing Ferroptosis

Dihydroartemisinin Sensitizes Lung Cancer Cells to Cisplatin Treatment by Upregulating ZIP14 Expression and Inducing Ferroptosis

ABSTRACT Background Despite significant advances in lung cancer treatment, cisplatin (DDP)‐based chemotherapy remains a cornerstone for managing the disease. However, the prevalence of chemoresistance presents a major challenge, limiting its effectiveness and contributing to poor outcomes. This unde...

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Bibliographic Details
Main Authors: Zhuoying Yang, Zehao Zhou, Qingyu Meng, Zhijie Chen, Liang Yun, Jianjun Jiang, Yujing He, Meijuan Dian, Ruihao Zhang, Haotian Ge, Tianbao Yan, Biying Men, Zichao Li, Xu Wu, Junming He, Shuan Rao
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Cancer Medicine
Subjects:
cisplatin
dihydroartemisinin
ferroptosis
lung cancer
non‐transferrin iron transport
ZIP14
Online Access:https://doi.org/10.1002/cam4.70271

Internet

https://doi.org/10.1002/cam4.70271

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