Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats

Altering Early Life Gut Microbiota Has Long-Term Effect on Immune System and Hypertension in Spontaneously Hypertensive Rats

Hypertension is regulated by immunological components. Spontaneously hypertensive rats (SHR) display a large population of proinflammatory CD161 + immune cells. We investigated the effect of early post-natal gut microbiota on the development of the immune system and resulting hypertension in the SHR...

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Bibliographic Details
Main Authors: Francois M. Abboud, Michael Z. Cicha, Aaron Ericsson, Mark W. Chapleau, Madhu V. Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
microbiome
immune system
gut microbiome
hypertension
SHR (spontaneously hypertensive rat)
T helper (T) 17 cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.752924/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.752924/full

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