Enzyme-controlled, nutritive hydrogel for mesenchymal stromal cell survival and paracrine functions

Abstract Culture-adapted human mesenchymal stromal cells (hMSCs) are appealing candidates for regenerative medicine applications. However, these cells implanted in lesions as single cells or tissue constructs encounter an ischemic microenvironment responsible for their massive death post-transplanta...

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Bibliographic Details
Main Authors: Cyprien Denoeud, Guotian Luo, Joseph Paquet, Julie Boisselier, Pauline Wosinski, Adrien Moya, Ahmad Diallo, Nathanael Larochette, Stéphane Marinesco, Anne Meiller, Pierre Becquart, Hilel Moussi, Jean-Thomas Vilquin, Delphine Logeart-Avramoglou, Adeline Gand, Véronique Larreta-Garde, Emmanuel Pauthe, Esther Potier, Hervé Petite
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05643-y