The Motility and Mesenchymal Features of Breast Cancer Cells Correlate with the Levels and Intracellular Localization of Transglutaminase Type 2

We have investigated motility in breast cancer cell lines in association with the expression of Transglutaminase type 2 (TG2) as well as upon the administration of Doxorubicin (Dox), an active cytotoxic agent that is employed in chemotherapy. The exposure of MCF-7 cells to the drug increased TG2 lev...

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Bibliographic Details
Main Authors: Nicoletta Bianchi, Federica Brugnoli, Silvia Grassilli, Karine Bourgeois, Jeffrey W. Keillor, Carlo M. Bergamini, Gianluca Aguiari, Stefano Volinia, Valeria Bertagnolo
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/11/3059