Calpain inhibition as a possible new therapeutic target in multiple sclerosis

Calpain inhibition as a possible new therapeutic target in multiple sclerosis

Multiple sclerosis (MS), the most common chronic autoimmune inflammatory disease of the central nervous system (CNS), is characterized by demyelination and neurodegeneration. In particular, neurodegeneration is a major factor in disease progression with neuronal death and irreversible axonal damage...

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Bibliographic Details
Main Authors: Amena W. Smith, Swapan K. Ray, Arabinda Das, Kenkichi Nozaki, Baerbel Rohrer, Naren L. Banik
Format: Article
Language:English
Published: AIMS Press 2017-10-01
Series:AIMS Molecular Science
Subjects:
inflammation
demyelination
neurodegeneration
oligodendrocytes
neurons
retinal ganglion cells
axonal degeneration
optic neuritis
calpain
calpain inhibition
Online Access:http://www.aimspress.com/Molecular/article/1672/fulltext.html

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http://www.aimspress.com/Molecular/article/1672/fulltext.html

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