DNA methylation: a cause and consequence of type 2 diabetes

DNA methylation is a relatively stable epigenetic modification that can regulate and stabilize gene expression patterns and hence establish cell identity. Because metabolic intermediates are key factors of DNA methylation and demethylation, perturbations in metabolic homeostasis can trigger alterati...

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Bibliographic Details
Main Author: Mirang Kim
Format: Article
Language:English
Published: BioMed Central 2019-11-01
Series:Genomics & Informatics
Subjects:
Online Access:http://genominfo.org/upload/pdf/gi-2019-17-4-e38.pdf