Molecular alterations and therapeutic targets in pancreatic neuroendocrine tumors

Human pancreatic neuroendocrine tumors (PanNETs) are a rare, deadly tumor type that is sporadic or arises in the background of a hereditary syndrome. A critical genetic event in sporadic tumors is inactivation of the gene menin 1 (MEN1) on chromosome 11, and indeed, PanNETs occur in patients with th...

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Bibliographic Details
Main Authors: Yarui Ma, Xiaoyue Wang, Hong Zhao, Yuchen Jiao
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2023-09-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000125