Molecular alterations and therapeutic targets in pancreatic neuroendocrine tumors
Human pancreatic neuroendocrine tumors (PanNETs) are a rare, deadly tumor type that is sporadic or arises in the background of a hereditary syndrome. A critical genetic event in sporadic tumors is inactivation of the gene menin 1 (MEN1) on chromosome 11, and indeed, PanNETs occur in patients with th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Health/LWW
2023-09-01
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Series: | Journal of Pancreatology |
Online Access: | http://journals.lww.com/10.1097/JP9.0000000000000125 |