Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells

ABSTRACT Sindbis virus (SINV [genus Alphavirus, family Togaviridae]) is an enveloped, mosquito-borne virus. Alphaviruses cause cytolytic infections in mammalian cells while establishing noncytopathic, persistent infections in mosquito cells. Mosquito vector adaptation of alphaviruses is a major fact...

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Bibliographic Details
Main Authors: Joyce Jose, Aaron B. Taylor, Richard J. Kuhn
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02294-16