A Horizontal Magnetic Tweezers and Its Use for Studying Single DNA Molecules

We report the development of a magnetic tweezers that can be used to micromanipulate single DNA molecules by applying picoNewton (pN)-scale forces in the horizontal plane. The resulting force–extension data from our experiments show high-resolution detection of changes in the DNA tether&am...

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Bibliographic Details
Main Authors: Roberto Fabian, Christopher Tyson, Pamela L. Tuma, Ian Pegg, Abhijit Sarkar
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Micromachines
Subjects:
Online Access:http://www.mdpi.com/2072-666X/9/4/188