Atorvastatin reduces contrast media-induced pyroptosis of renal tubular epithelial cells by inhibiting the TLR4/MyD88/NF-κB signaling pathway

Abstract Background Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital-acquired renal failure. However, there is no effective treatment of CI-AKI, and its mechanism is unknown. Interestingly, atorvastatin has been reported to be effective in renal injury. Theref...

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Bibliographic Details
Main Authors: Rong-zheng Yue, Ya-juan Li, Bai-hai Su, Cong-jun Li, Rui Zeng
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-023-03066-9