Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response.

Head and neck squamous cell carcinoma (HNSCC) is a major cause of morbidity and mortality underscoring the need for safe and effective chemopreventive strategies. Targeting epidermal growth factor receptor (EGFR) is attractive in that it is an early critical event in HNSCC pathogenesis. However, cur...

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Bibliographic Details
Main Authors: Ramesh K Wali, Dhananjay P Kunte, Mart De La Cruz, Ashish K Tiwari, Jeffrey Brasky, Christopher R Weber, Tina P Gibson, Amir Patel, Suzana D Savkovic, Bruce E Brockstein, Hemant K Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3366973?pdf=render