Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infectionResearch in context

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infectionResearch in context

Summary: Background: CD8+ T cells equipped with a full arsenal of antiviral effector functions are critical for effective immune control of HIV-1. It has nonetheless remained unclear how best to elicit such potent cellular immune responses in the context of immunotherapy or vaccination. HIV-2 has b...

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Bibliographic Details
Main Authors: Mariela P. Cabral-Piccin, Laura Papagno, Xavier Lahaye, Federico Perdomo-Celis, Stevenn Volant, Eoghann White, Valérie Monceaux, Sian Llewellyn-Lacey, Rémi Fromentin, David A. Price, Nicolas Chomont, Nicolas Manel, Asier Saez-Cirion, Victor Appay
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:EBioMedicine
Subjects:
CD8+ T cells
HIV-1
HIV-2
STING
Type I IFN
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001226

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http://www.sciencedirect.com/science/article/pii/S2352396423001226

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